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3.3K views · 181 reactions | Reductive Amination Mechanism Examples | Advanced Organic Chemistry: Reaction Mechanism, Strategy, Applications. | Facebook
Advanced Organic Chemistry: Reaction Mechanism, Strategy, Applications.. . Reductive Amination Mechanism Examples
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Reductive Amination Mechanism
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SOLVED:One problem with reductive amination as a method of amine synthesis is that by-products are sometimes obtained. For example, reductive amination of benzaldehyde with methylamine leads to a mixture of N -methylbenzylamine and N -methyldibenzylamine. How do you suppose the tertiary amine by-product is formed? Propose a mechanism.
SOLVED:One problem with reductive amination as a method of amine synthesis is that by-products are sometimes obtained. For example, reductive amination of benzaldehyde with methylamine leads to a mixture of N -methylbenzylamine and N -methyldibenzylamine. How do you suppose the tertiary amine by-product is formed? Propose a mechanism.
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