GitHub

Scripts to make cryo-electron tomography a bit easier

blend-montages: Blends SerialEM montages, write results to separate folder. Example: tomotools blend-montages MMM*.mrc montages-blended preprocess: Prepare tiltseries for reconstruction. Takes data ...
gut.bmj

Characterisation of plasmablast-derived HBsAg-specific antibody and its structural basis for binding to native HBsAg dimer

Background Plasmablast-derived HBV surface antigen (HBsAg)-specific monoclonal antibody (mAb) and structural basis for binding to native HBsAg are poorly known. Objective We aimed to identify ...
C&EN

MicroED as a Powerful Tool for Structure Determination of Macrocyclic Drug Compounds Directly from Their Powder Formulations

Howard Hughes Medical Institute, University of California Los Angeles, Los Angeles, California 90095, United States Department of Biological Chemistry, University of California Los Angeles, 615 ...
C&EN

Molecular Basis of the Electron Bifurcation Mechanism in the [FeFe]-Hydrogenase Complex HydABC

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...
eLife

Inhibition of the proton-activated chloride channel PAC by PIP

The recently identified Proton-Activated Chloride (PAC) channel is ubiquitously expressed and has important roles in intracellular organelles and its function in the plasma membrane is associated with ...
Frontiers

U-RISC: An Annotated Ultra-High-Resolution Electron Microscopy Dataset Challenging the Existing Deep Learning Algorithms

Connectomics is a developing field aiming at reconstructing the connection of the neural system at the nanometer scale. Computer vision technology, especially deep learning methods used in image ...
eLife

A modular platform for automated cryo-FIB workflows

Lamella micromachining by focused ion beam milling at cryogenic temperature (cryo-FIB) has matured into a preparation method widely used for cellular cryo-electron tomography. Due to the limited ...
Europe PMC

Structure of the human SAGA coactivator complex.

Either your web browser doesn't support Javascript or it is currently turned off. In the latter case, please turn on Javascript support in your web browser and reload ...
Frontiers

Serial Electron Diffraction Data Processing With diffractem and CrystFEL

Serial electron diffraction (SerialED) is an emerging technique, which applies the snapshot data-collection mode of serial X-ray crystallography to three-dimensional electron diffraction (3D Electron ...
ahajournals.org

Cryo-Electron Microscopy Structure of the αIIbβ3-Abciximab Complex

The αIIbβ3 antagonist antiplatelet drug abciximab is the chimeric antigen-binding fragment comprising the variable regions of murine monoclonal antibody 7E3 and the constant domains of human IgG1 and ...
PNAS

Structural and functional analyses of photosystem II in the marine diatom Phaeodactylum tricornutum

Despite distinctions in the architecture of thylakoid membranes, the fundamental machinery responsible for photosynthetic electron transfer is highly conserved in all oxygenic organisms. Using ...