ZFTA-RELA (Zinc Finger Translocation Associated – RELA Proto-Oncogene) fusion-positive ependymomas are lethal pediatric brain tumors lacking targeted therapies. By integrating large-scale human tumor ...
Atherosclerotic cardiovascular disease, characterized by an imbalanced lipid metabolism and a dysregulated immune response, is a major cause of death worldwide. The AhR (aryl hydrocarbon receptor) is ...
Recent advances in spatial omics technologies have enabled new approaches for analyzing tissue morphology, cell composition, and biomolecule expression patterns in situ. These advances are promoting ...
aUnitat de Recerca Biomèdica, Hospital Universitari de Sant Joan, Universitat Rovira i Virgili, Institut d’Investigació Sanitària Pere Virgili, Reus, Spain ...
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Head of Oncology; Assoc. Professor in Surgical Oncology; Consultant General & Hepato-Pancreato-Biliary (HPB) Surgeon Professor Adam Frampton is a surgeon-scientist and Consultant General and ...
Single-cell omics aim at charting the different types and properties of all cells in the human body in health and disease. Over the past years, myriads of cellular phenotypes have been defined by ...
In diabetic patients, dyslipidemia frequently contributes to organ damage such as diabetic kidney disease (DKD). Dyslipidemia is associated with both excessive deposition of triacylglycerol (TAG) in ...
Estrogen receptor α (ERα) is a transcription factor that induces cell proliferation and exhibits increased expression in a large subset of breast cancers. We comprehensively searched for indicators of ...
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