Interferon receptor knockout chickens uncover how type I and III interferons differentially shape avian antiviral immunity and influenza disease outcomes.

Objectives: Anti-citrullinated peptide antibodies (ACPAs) are established as useful predictors of radiographic progression in rheumatoid arthritis (RA). The main objective of this study was to test ...

Polymorphisms in the gene SLC6A3 for the dopamine transporter (DAT) have been associated with DAT availability in the human brain. This finding suggests an effect of these polymorphisms, or of ...

Objective Distinguishing early dilated cardiomyopathy (DCM) from physiological left ventricular (LV) dilatation with LV ejection fraction <55% in athletes (grey zone) is challenging. We evaluated the ...

Gene expression profiles, including those from 35 LDH patients and 43 healthy volunteers, were downloaded from the GEO database (GSE124272, GSE150408, GSE23130, GSE153761). After merging four ...

Obesity is a complex condition that is affected by a variety of factors, including the environment, behavior, and genetics. However, the genetic mechanisms underlying obesity remains poorly elucidated ...

Introduction The success rate of in vitro fertilisation (IVF) treatment for couples with infertility remains low due to lack of a reliable tool in selecting euploid embryos for transfer. This study ...

The effect of alirocumab, a PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitor, on coronary plaque burden in patients with familial hypercholesterolemia has not been addressed. Our aim ...

aNational Institute of Diabetes and Digestive and Kidney Diseases, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA bSurgical Oncology Program, National Cancer Institute, ...

Dynamical systems have been used to model the paroxysmal nature of seizures in epilepsy. In parallel, seizures have been discovered to occur with cyclical periodicity in epilepsy, occurring at ...

Higher plants produce specialized metabolites to cope with biotic and abiotic challenges faced in natural environments. The diversity and complexity of specialized metabolism is often beneficial, ...