The kinetochore is a large proteinaceous structure that mediates interactions between chromosomal DNA and spindle-microtubule polymers. More than 80 kinetochore proteins have been identified using ...
In both HEC-1-A and ISK cells, alectinib significantly reduced intracellular heme content compared with the solvent control (P < 0.05). Combination with 20 μM ALA further decreased heme levels, which ...