Isotope labeling is a fundamental technique in chemistry and biochemistry for investigating molecular structures, reaction mechanisms, and metabolic pathways. The accurate determination of isotope ...
The tumor microenvironment (TME) is a complex mixture, with diverse cell type interactions. Due to the variability of expression patterns within and across cell types, accurately inferring cell type ...
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Protein mass spectrometry imaging (MSI) with electrospray-based ambient ionization ...
Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, Brisbane 4102, Australia Van ’t Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, ...
Here, we present a comprehensive and high-resolution tissue methylation atlas and a deep neural network (DNN)-based model named cfSort for quantifying tissue composition sensitively and robustly in ...
Spatial transcriptomics technologies generate gene expression profiles with spatial context, requiring spatially informed analysis tools for three key tasks, spatial clustering, multisample ...
Background: More than 150 types of brain tumors have been documented. Accurate diagnosis is important for making appropriate therapeutic decisions in treating the diseases. The goal of this study is ...