Optical tweezers have been instrumental to the determination of mechanical parameters of molecular motors. This study by Takamatsu et al. reports key mechanical parameters of kinesin KIF1A using ...
Use 3D beacon network to search for any type of structure (measured or predicted) of given uniprot accessions. Filter AlphaFoldDB structures based on confidence (pLDDT). Keeps entries with requested ...
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Aptamers, single-stranded nucleic acids that fold into unique three-dimensional shapes ...
BEER is a desktop application for integrated biophysical analysis of protein sequences. It accepts a sequence (pasted, imported as FASTA/PDB, or fetched from UniProt/RCSB), runs 14 classical analysis ...
The most widely accepted DNA structure is the classical B-DNA form, which is a right-handed double helix in nature and contains the hydrogen bonds between the nucleobases as described by Watson and ...
The Smc5/6 complex plays multiple roles in DNA replication and repair. Its genome-protecting functions rely on its interaction with DNA; however, how this complex engages DNA is poorly understood. We ...
The 3D architectures of RNAs are essential for understanding their cellular functions. While an accurate scoring function based on the statistics of known RNA structures is a key component for ...
With the growth of protein structure data, the analysis of molecular interactions between ligands and their target molecules is gaining importance. PLIP, the protein-ligand interaction profiler, ...