TRRAP links Myc with histone acetylases and appears to be an important mediator of its oncogenic function. Here we show that interaction with TRRAP is required for cellular transformation not only by ...
We previously described two nuclear cofactors, TRRAP and TIP49, that have functional roles in Myc-mediated oncogenesis. We have now expanded the analysis of these Myc-associated cofactors to ...
NHGRI-led researchers suggest glutamate signaling pathway could represent new target for skin cancer therapeutics. A whole-exome sequencing project has generated what researchers claim is the most ...
Oncotarget published "Luminescence complementation technology for the identification of MYC:TRRAP inhibitors" which reported that the fact that many cancer cells cannot survive without MYC – a ...
Just as diamond ring is needed in marriage, NuA4/Tip60, a complex with diamond ring architecture, is required for regulatory and repairing processes. Prof. CAI Gang and Prof. Jacques Côté's team ...
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