The Tas protein uses an RNA guide to recognize a specific target DNA sequence. A vast search of natural diversity has led scientists at MIT’s McGovern Institute and the Broad Institute of MIT and ...

Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA. Researchers led ...

The approval of messenger RNA (mRNA) based COVID-19 vaccines marked a pivotal scientific milestone, establishing mRNA as an innovative drug modality with immense therapeutic potential. However, due to ...

The human body has to protect itself from pathogens and infectious agents, and there are a variety of ways for the immune system to sense foreign invaders, and react to the threats they may pose. But ...

(Nanowerk News) In a leap forward for genetic engineering, a team of researchers from the Arc Institute have discovered the bridge recombinase mechanism, a precise and powerful tool to recombine and ...

A new method of making cancer cells more visible to the immune system could improve how well immunotherapy works against a range of different tumors, potentially leading to more effective treatment ...

Mammalian immunity has long been thought to rely solely on proteins and specialized immune cells. However, a newly proposed concept—RNA immunity—is reshaping this perspective. In a recent publication ...

Two new technologies—an AI diagnostic system called DeepRare and a targeted long-read RNA sequencing platform named STRIPE—are showing promise in diagnosing rare diseases that evade standard tests.

Victor Ambros from the University of Massachusetts Chan Medical School and Gary Ruvkun from Harvard Medical School have won the 2024 Nobel Prize in Physiology or Medicine. They share the prize for ...