Chemokines, acting as "traffic controllers" in the tumor microenvironment, regulate immune cell infiltration and local ...

Abnormal cell proliferation is a major hallmark of cancer. Several proteins are involved in the cell cycle, and most of these regulate the positive or negative control of cyclin-dependent kinases.

Macrophages, key regulators of tissue health and immune defense, are among the most abundant immune cells in solid tumors. Their role in cancer has been difficult to define because even closely ...

Calidi Biotherapeutics, Inc. (NYSE American: CLDI) (“Calidi” or the “Company”), a biotechnology company pioneering the development of targeted genetic medicines, presented new data at the American ...

There is a challenge related to prostate and many other cancers that cancer cells form resistance to treatments as the disease progresses. However, these resistance mechanisms are not yet fully ...

The tumor microenvironment (TME) is one of the most formidable obstacles in the fight against cancer. While therapies that target cancer cells have been revolutionary, many patients still do not ...

A study demonstrates that levels of the CTHRC1 protein in tumor-associated fibroblasts can predict immunotherapy outcomes in ...

A study identifies tumor cells with metastatic potential within primary tumors, showing Prrx1 gene levels control invasion, ...

Understanding which cells within a tumor will go on to form metastases remains one of the major challenges in cancer research ...