For decades, we've been told “Lower LDL is Better.” But what if, in our myopic obsession with LDL and ApoB, we’ve missed a ...

Familial hypobetalipoproteinemia (FHBL), caused by apolipoprotein B (APOB) variants, disrupts APOB-containing lipoprotein synthesis, leading to reduced serum total cholesterol, low-density lipoprotein ...

Familial Hypobetalipoproteinemia (FHBL), caused by variants in the apolipoprotein B (APOB) gene, is a rare autosomal co-dominant monogenic disorder characterized by lifelong low plasma levels of total ...

“Bad,” or LDL, cholesterol is a major risk factor for heart disease and most people are screened for it as part of their yearly physicals. There’s another marker in the blood that may be a better ...

Monthly olezarsen reduced triglycerides and apolipoprotein B in patients with hypertriglyceridemia but may have no impact on ...

“You are going to die young.” The first time I heard those six words, they were jarring. And I chuckle when I hear them.

Scientists are rethinking how to treat a widespread genetic cholesterol disorder by targeting particle production instead of ...