Timing of troughs Troughs should be obtained at steady state: approximately prior to the fifth dose IIB Optimal trough concentrations Should be >10 mg/l at a minimum to avoid development of ...

Jennifer Le, PharmD Pediatric patients who attain higher trough levels of the drug may be at higher risk of kidney damage. SAN FRANCISCO—Nephrotoxicity from vancomycin therapy develops more quickly in ...

VANCOMYCIN is a penicillinase-resistant antibiotic that may be used in the treatment of staphylococcal infections. Because it is known to be excreted chiefly through the kidneys in normal persons 1 ...

The vancomycin monitoring guidelines did not specifically address patients with several conditions such as severe renal dysfunction which might impact proper dosing. Vandecasteele and De Vriese ...