A review on claudins and tight junctions. Tight junctions along the nephron play a critical role in regulating the reabsorption of ions such as sodium and chloride. But what is th ...

Our bodies and organs are shielded from the external environment by tissue barriers like the skin. These barriers must be tightly sealed to prevent unwanted substances from entering. This sealing is ...

Cells in humans and all vertebrates are tightly packed together to form organs and glands — tissues essential for living, breathing and moving. “In humans, three families of membrane proteins in ...

As a human embryo grows, a set of molecules directs cells as they multiply and take on specific identities and spatial positions within the embryo. In one crucial step known as gastrulation, these ...

Barriers between stem cells play a crucial role in human development—and offer a new potential route for fertility treatment SAN FRANCISCO, CA—As a human embryo grows, a set of molecules directs cells ...

Cell-to-cell junctions were visualized by ZO1-GFP, and the dynamics of cell junctions were captured by movies. When the cells indicated by * were spontaneously stretched, a continuous belt of cell ...

Our skin and mucous membranes are protected by epithelial cells. This barrier tissue performs its function thanks to specialized structures called junctions. They ensure cell cohesion and regulate ...