Sometimes, in genetics, two wrongs do make a right. A research team has recently shown that two harmful genetic variants, ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave. Researchers have now mapped this hidden architecture in unprecedented detail, showing ...

We know the genes, but not their functions—to resolve this long-standing bottleneck in microbial research, a joint research team has proposed a cutting-edge research strategy that leverages artificial ...

A new resource from the Gene Ontology Consortium, a comprehensive encyclopedia of the known functions of all protein-coding human genes, has been completed and released on a new website. For the first ...

No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders. These maps detail ...

We know the genes, but not their functions.” To resolve this long-standing bottleneck in microbial research, a joint research ...

Elizabeth Kellogg, PhD, St. Jude Department of Structural Biology, used cryo-EM to study the evolutionary journey of Fanzor2, a compact eukaryotic genome-editing protein with huge potential. (MEMPHIS, ...