Throughout the course of human history, one infectious disease (Figure 1) may account for more deaths than any other, perhaps all others combined. Smallpox mortality falls between 20% and 50%. Until ...

Oct. 19 -- Smallpox was one of the deadliest diseases ever to afflict the human race, until a worldwide effort succeeded in eradicating it from the planet 25 years ago. But the events of the past few ...

Smallpox inoculation (variolation) was widely reported in sub-Sahara Africa before, during, and after the colonial era. The infective smallpox materials and techniques used, as well as the anatomical ...

For permission requests, please contact NEJM Reprints at [email protected] ...