Protein trafficking is a fundamental cellular process that ensures efficient sorting, modification, and delivery of proteins to their correct subcellular destinations. At its core, this process ...

Using state-of-the-art cell imaging and genome editing technology, scientists have begun to unravel how this collection of proteins performs its essential service. The discovery could eventually help ...

For Amy Engevik, an epithelial cell biologist at the Medical University of South Carolina who studies cell function in the gastrointestinal tract, protein location matters more than abundance. She ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...

This illustration shows how the membrane trafficking protein VAMP72 gradually changed during plant evolution to give rise to VAMP727, which functions in transporting storage proteins to vacuoles. The ...