A group of international researchers reports the availability of a new “map”’ of every gene, protein, and metabolic pathway required for a cell to efficiently secrete recombinant proteins. The team, ...
A single damaged protein inside one brain cell may seem insignificant. Yet new research shows how that small mistake can ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
Seed round co-led by Elaia, Pfizer Ventures and Bpifrance Machine-learning platform enables signal peptide-informed discovery of small molecules that selectively inhibit protein secretion allowing for ...
Some dietary supplements may help naturally boost GLP-1, but more research is needed to better understand their potential ...
snoRNAs were thought simply to guide chemical modifications to rRNAs, but a new technique has revealed a suite of potential functions in protein secretion. A recent research effort from the University ...
Researchers at the University of Chicago have developed a technology for identifying new cellular RNA targets of small nucleolar RNAs (snoRNAs), a common but overlooked group of guide RNA molecules ...
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