PrfA, the Ace in the Hole for L. monocytogenes Intracellular Survival In addition to the lysine substitution mutations within the putative PrfA cofactor-binding pocket, one additional mutation has ...
Michael Hall, Christin Grundström, Afshan Begum, Mikael J. Lindberg, Uwe H. Sauer, Fredrik Almqvist, Jörgen Johansson, A. Elisabeth Sauer-Eriksson Proceedings of the National Academy of Sciences of ...
In the food-borne pathogen Listeria monocytogenes, virulence genes are expressed at 37°C, but not 30°C. This process is under the control of PrfA — a transcriptional activator thermoregulated by a ...
In Early Recurrent Liver Cancer, Surgery and Radiofrequency Ablation Spark Similar Survival Benefits
Radiofrequency ablation was statistically on par with surgery when it came to survival after an early recurrence of liver cancer, but surgery provided more benefit if the disease was a bit more ...
Intracellular pathogens are responsible for much of the world-wide morbidity and mortality due to infectious diseases. To colonize their hosts successfully, pathogens must sense their environment and ...
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