Researchers have discovered a new mechanism for potassium channel inhibitor entry, which could improve the specificity of drugs targeting the channel. Upon binding to calcium ions, BK channels allow ...

Following this design principle, the researchers create angstrom-scale pores in bi-layer graphene sheets, and decorate the two pore edges with twisted rings of carbonyl groups. The artificial ion ...

Large-conductance calcium-activated potassium (BK) channels are critical determinants of smooth muscle function by mediating rapid feedback between intracellular calcium levels and membrane potential.

A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function with a “ball-and-chain” channel-plugging mechanism, according to investigators ...

Underlying every thought, heartbeat and movement are ion channels, busily conducting high-speed streams of ions into cells, like subway trains coursing through tunnels. Ion channels span the cellular ...