A team from Würzburg has fundamentally changed our understanding of platelet biology. The researchers demonstrate that the ...
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Scientists discover a non-classical platelet mechanism linked to severe infections
Platelets are small, anucleate blood cells that play an essential role in hemostasis. Their primary task is to recognize vascular injury, become activated, and aggregate via their surface receptor ...
A team from the Würzburg Institute of Experimental Biomedicine I and the Rudolf Virchow Center (RVZ) has fundamentally changed our understanding of ...
Ado-trastuzumab emtansine (T-DM1) treatment results in grade 3-4 thrombocytopenia in 8%-13% of patients. Prior in vitro studies reported T-DM1 inhibition of megakaryocyte maturation as the cause of ...
Managing drug dosage is critical to the overall success of pharmaceutical intervention, not only in the clinic but also in clinical trials. Inadequate dose management of certain drugs can have fatal ...
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