Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia. How this happens remains largely ...

Family with sequence similarity 19 member A5 (FAM19A5) is a secretory protein highly expressed in the brain that regulates synapse dynamics through its interaction with leucine-rich repeat-containing ...

Scientists from Oregon Health & Science University (OHSU) and the University of Edinburgh have discovered that a little-understood junction that connects neurons to oligodendrocyte precursor cells ...

Clinical portfolio, informed by deep and novel synapse biology and pharmacology insights, aims to strengthen neural connections through event-driven pharmacology Lead candidate zelquistinel is ...

The Noelin family of secreted proteins bind to the external portion of AMPA glutamate receptors and stabilize them on the neuronal cellular membrane, a process necessary for transmission of ...

An integrated spiking artificial neuron, with rich neuron functionality, single-transistor footprints, and low energy consumption for neuromorphic computing systems, can be created by stacking one ...

The brain’s rules seem simple: Fire together, wire together. When groups of neurons activate, they become interconnected. This networking is how we learn, reason, form memories, and adapt to our world ...

The human brain contains nearly 86 billion neurons, constantly exchanging messages like an immense social media network, but neurons do not work alone – glial cells, neurotransmitters, receptors, and ...