Longevity science has spent decades chasing single molecules that might slow aging, but most candidates have delivered modest, inconsistent results. A new line of research is now pointing to a ...

Scientists uncovered how the amino acid leucine enhances mitochondrial efficiency by preserving crucial proteins that drive energy production. By downregulating the protein SEL1L, leucine prevents ...

(Philadelphia, PA) – Calcium transport into and out of mitochondria – the powerhouses of cells – is central to cellular energy production and cell death. To maintain the balance of calcium within ...

A research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating ...

Newly reported research in human tissue and in mice has uncovered a mechanism by which brown fat (brown adipose tissue; BAT) is converted into heat, and identified a control protein that may represent ...

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...