Scientists have long known that inherited neurodegenerative disorders, including Alzheimer's, Parkinson's or motor neuron ...

Microtubules, a key component of the cytoskeleton in eukaryotic cells, serve as scaffolds and play vital roles in cellular processes such as cell division, cell migration, intracellular transport, and ...

Throughout our bodies, most of our organs are maintained and repaired through regulated cell division, where new cells replace old ones that are lost or damaged. Before a cell divides, it executes a ...

Researchers have identified a mechanism which can explain aspects of neurodegeneration which have baffled scientists for ...

A multi-institutional research collaboration has revealed that the microtubule network (*1), which plays a vital role in cell construction and polarization (*2), utilizes the phase separation (*3) ...

Prefoldin 5 stabilises neuronal microtubules and suppresses Tau-mediated neurotoxicity, offering a potential therapeutic target for tauopathies.

A joint research team from the LKS Faculty of Medicine (HKUMed) and the Faculty of Science at the University of Hong Kong has uncovered an unexpected interaction between chemotherapeutic agents and a ...

Microtubule-depolymerising agents disrupt microtubule function by binding to specific sites on β-tubulin subunits; consequently they are ideal for use in cell synchronization studies and also in the ...

Identifying the primary site using gene expression profiling in patients with carcinoma of an unknown primary (CUP): a feasibility study from the GEFCAPI ...