Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year. A growing body of evidence now ...

However,instead of attacking cancer cells, they are typically co-opted to support tumor growth, metastasis, and therapeutic ...

Metabolic reprogramming in neuroinflammation refers to dynamic shifts in cellular energy pathways that underpin the activation, function and fate of central nervous system immune cells, principally ...

Tumor-associated macrophages (TAMs) are immune cells that tumors hijack to fuel their own growth and evade immune attack. A ...

AbstractNon apoptotic cell death programs particularly ferroptosis and cuproptosis are transforming how we understand cancer ...

Breast cancer development is not solely the result of cancer cells acting independently, it involves a dynamic and complex ecosystem composed of cancer cells, immune cells, fibroblasts, adipocytes, ...

Aerobic glycolysis dominates lesion bioenergetics, with lactate promoting histone lactylation, M2 macrophage polarization, CD8⁺ T-cell exhaustion, EMT, and fibrosis that reinforce immune-protected ...

A first-in-class antisense oligonucleotide — RES-010 (Resalis Therapeutics, Turin, Italy) — may complement and enhance the efficacy of antiobesity drugs such as GLP-1 receptor agonists (RAs), ...

Leuven, 11 March 2025 – Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center ...