The World Health Organization (WHO) has published its new 2025 Guidelines on the replacement or removal of animal tests for the quality control of biological products.

Every year in May when high tide coincides with the full moon, horseshoe crabs convene on the beaches of the mid-Atlantic coast to lay millions of eggs. At the same time, migratory shorebirds on their ...

A chemical compound found in the blood of horseshoe crabs is widely used in the biomedical community to test for the presence of bacterial exposure or infection. This limulus amebocyte lysate (LAL) ...

New standards may help push more drugmakers to use a synthetic product for critical drug safety testing, instead of one made from horseshoe crab blood that has long drawn criticism. The U.S.