A new study reveals that age-related changes in the gut microbiota directly impair intestinal stem cell (ISC) function and that restoring a youthful microbial environment can reverse this decline.

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...

Tuft cells are present throughout the intestinal tract as well as in many organs. Studies in mice have shown that when tuft cells sense the presence of pathogens, they signal to immune cells and to ...

A human intestinal organoid, displaying typical ‘budding crypts’ and a central ‘villus-like’ domain. The main intestinal cell types are shown in green, blue, red and purple. Membranes are yellow and ...

The trillions of microbes in our gastrointestinal tract, known as the gut microbiome, are crucial to the body; the gut microbiome aids in digestion, nutrient absorption, and influences our health in ...

Gut support cells communicate with surprising precision – like brain neurons – using tiny extensions to send instructions to the stem cells responsible for maintaining and healing the intestine. The ...