In 2021, a research team discovered the insulin-inhibitory receptor 'Inceptor' and its role as a suppressor of the insulin signaling pathway. Now, the researchers have unlocked another, even more ...

Developing resistance to insulin is a key step on the road to diabetes, making insulin resistance a target for treating metabolic dysfunction. Insulin orchestrates blood glucose levels by signaling ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...

The insulin receptor (IR) is a prototypical receptor tyrosine kinase that orchestrates critical cellular processes, including metabolism, cell growth and differentiation. Activation of the IR involves ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study by a team at the Max Planck Institute ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...

Researchers from the German Diabetes Center (DDZ) and the Heinrich Heine University Düsseldorf (HHU) have studied the temporal pattern of insulin action on protein kinases in human muscle cells in ...

Study: Personalized molecular signatures of insulin resistance and type 2 diabetes. Image credit: Microgen/Shutterstock.com A recent study, published in the journal Cell, utilized cutting-edge ...

Overview of peripheral and central insulin actions (black arrows). The vast majority of insulin hormones are synthesized by the pancreas. Insulin crosses the blood‒brain barrier (BBB) to act within ...