Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

For decades, dogma dictated that the immune system consisted of two separate branches. Cells of the innate system respond rapidly to molecular patterns shared by a broad array of pathogens. Meanwhile, ...

Novel research led by Brazilian scientists describes the immune system's reactions in detail in the first living patient to ...

A section of Goodsell et al.’s magnificent “Integrative illustration for coronavirus outreach” highlighting the packaging of the viral genetic material (in pink) by the scaffold “nucleocapsid protein” ...

Research reveals that T cells from the adaptive immune system can manipulate the memory of innate immune cells. Previously, it was believed that the memory of innate immune cells operated ...

Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the GI tract. The two major types of IBD are Crohn's disease (CD) and ulcerative colitis (UC). Whereas in UC inflammation ...

A novel tumor suppressor, BATF2, can be silenced by factors in the tumor microenvironment, leading to a reduced immune ...

The interferon regulatory factor (IRF) family of transcription factors, pivotal for initiating antiviral type I interferon ...

Cancer immunotherapies, including cancer vaccines, harness and amplify the immune system’s natural ability to detect and attack cancer cells. In this illustration, immune T cells (pink) attach to a ...