Obesity associated with hypothalamic dysfunction was initially described in patients with craniopharyngioma. Hypothalamic obesity may also result from brain radiation, infection (eg, tuberculosis), ...

The GI tract is the body's largest endocrine organ and releases a plethora of regulatory peptide hormones that influence a number of physiological processes. The majority of these hormones are ...

Imcivree is Rhythm’s only approved drug and the company is now looking forward to an FDA approval for the drug in the ...

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus. In 2022, ...

A brand new candidate for weight-loss treatment is on the table, with scientists uncovering for the first time how a hormone produced by the hypothalamus during sleep has a direct impact on appetite ...

New research reveals how extracellular matrix (ECM) buildup in the brain’s hypothalamus leads to insulin resistance, paving the way for innovative therapies targeting obesity and diabetes. Study: ...

Hypothalamic obesity is a complex condition that doesn’t always respond to traditional weight loss methods. Medications, hormonal therapy, and surgery may be necessary to see results. Hypothalamic ...

Transcriptomic and genomic mutations reveal the mechanistic basis of timing seasonal life history transitions.

Q4 2025 preliminary net product revenues from global sales of IMCIVREE ® (setmelanotide) of approximately $57 million for the fourth quarter of 2025, an 11% increase over Q3 2025 -- -- FY 2025 ...