In a recent study published on the medRxiv* preprint server, researchers combined severe acute respiratory syndrome coronavirus (SARS-CoV-2) spike receptor-binding domain (RBD) protein vaccination ...
Antibodies are a critical feature of the human adaptive immune response. New immunotherapies require the production of selective and non-autoimmunogenic antibodies. These engineered antibodies can ...
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In the rapidly advancing field of immuno-oncology research, there has been increasing focus on the utility and optimization of cell humanized mice for translational research. Conventional murine ...
Due to advancements in genetic engineering, small animal models are continuing to change in response to market needs. Model developers strive to better reflect the role of this important asset in both ...
Purpose: The pharmacology, efficacy, dosage, adverse events, and economics of omalizumab are discussed. Summary: Omalizumab, a recombinant DNA-derived humanized monoclonal antibody, binds to the Cε3 ...
Why do 80 to 90% of people infected with COVID-19 experience only mild cases while 10 to 20% face more severe or life-threatening symptoms? Researchers in the lab of Yale’s Richard Flavell decided to ...
A recent study explored the therapeutic potential of hu128.1, a humanized antibody targeting transferrin receptor 1 (TfR1), in treating erythroleukemia using xenograft mouse models. The results ...
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