The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...

The overexpression of a gene tied to cell division and the structure and function of neurons may prevent and protect against cognitive decline in both mice and humans with Alzheimer's disease (AD), ...

Sometimes, in genetics, two wrongs do make a right. A research team has recently shown that two harmful genetic variants, ...

We know the genes, but not their functions—to resolve this long-standing bottleneck in microbial research, a joint research ...

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders. These maps detail ...

Chromosomes are thread-like structures comprising DNA that are present inside the nucleus of every cell in the body. Specific segments of DNA are called genes. Every chromosome contains many genes, ...

No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...

We know the genes, but not their functions.” To resolve this long-standing bottleneck in microbial research, a joint research ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...