Telomerase promotes proliferation of resting stem cells through a mechanism that does not involve the extension of chromosomal telomeres, researchers report in Nature this week. "This is a completely ...
Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres - regions of repetitive DNA sequences and a protein structure - protect the tips of chromosomes from damage. Every ...
A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they divide, a key process in keeping cells healthy. Using yeast, the researchers ...
Scientists investigate human telomere length to elucidate aging and diseases such as cancer and neurodegenerative disorders. In normal mammalian cells, a small telomeric DNA segment is lost after each ...
Telomere shortening is a potential diagnostic tool for differentiating ILD types, particularly in idiopathic pulmonary fibrosis (IPF). Genetic mutations in telomerase genes, such as TERC and TERT, ...
In the quest to unlock the secrets of aging and longevity, telomeres have emerged as key players. These protective caps at the ends of our chromosomes play a critical role in cellular aging. With each ...