Downstream sample preparation for subsequent quality attribute analysis represents “a significant bottleneck in process development for non-antibody biologics,” wrote Kevin Brower, PhD, global head of ...

Weak protein interactions between ubiquitin and the ubiquitin-proteasome system (UPS) enzymes that mediate its covalent attachment to substrates serve to position ubiquitin for optimal catalytic ...

University of Groningen scientists observed the characteristics of a single enzyme inside a nanopore. This revealed that the enzyme can exist in four different folded states, or conformers, that play ...

Scientists have developed a superior method for immobilizing enzymes on surfaces, deftly controlling their orientation, improving their efficiency and rendering them more stable. Virtually all ...