Jorge Manchola, a retired Air Force staff sergeant, was diagnosed with stage 4 lung cancer in 2023. The cancer had spread to ...

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

One of the most challenging moments in cancer treatment comes when a therapy stops working. In many metastatic cancers, drugs that are initially effective lose their potency over time, as malignant ...

Researchers working on an incurable blood cancer can now use a new lab model that could make testing potential new treatments and diagnostics easier and quicker, new research has found. Working with ...

Hereditary breast cancer results from inherited mutations, primarily in BRCA1 and BRCA2, increasing lifetime cancer risk. Additional genes like TP53, PTEN, PALB2, CHEK2, and ATM also contribute to ...

One in 6 patients with colorectal cancer have an inherited cancer-related gene mutation which likely predisposed them to the disease, according to a Mayo Clinic study. About 16 percent of the 361 ...

About one in five patients with cancer who undergo genetic testing are incidentally found to have mutations in their blood ...

Childhood cancers are often considered genetically simple, containing few mutations. However, this notion has been challenged in a new study that found an unexpectedly high number of mutations in a ...

Cancer survival rates climbed significantly in recent decades. But federal funding cuts could threaten that progress, ...