Which genes are required for turning embryonic stem cells into brain cells, and what happens when this process goes wrong? In a new study published today in Nature Neuroscience, researchers led by ...

A large genetic screen has revealed how stem cells transform into brain cells, exposing hundreds of genes that make this ...

The study used large-scale CRISPR gene-editing technology to systematically determine which genes are required as embryonic stem cells develop into brain cells.

Revvity's Dharmacon All-in-one lentiviral platform has expanded to include whole-genome library options for CRISPR knockout (CRISPRko), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa).

Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to knockout ...

A new publication from CorriXR Therapeutics, an oncology focused biotherapeutics company developing genetic medicines to overcome drug resistance in solid tumors, shows that its novel CRISPR-directed ...

“While recent single-cell multiomics studies and CRISPR screens in murine NK cells have expanded our understanding, actionable genomic targets in primary human NK cells have remained largely ...

A research team led by Prof. TAN Weihong and Prof. WU Qin from the Hangzhou Institute of Medicine (HIM) of the Chinese Academy of Sciences has developed a pioneering, multi-modal platform called SPARK ...