Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA, plays ...
In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A ...
What eventually becomes a graduate student’s PhD thesis work is rarely the project they initially pursued. However, in rare cases like with recent PhD graduate Dr. April Lo from Dr. Alice Berger’s Lab ...
TAMPA, Fla. — Pancreatic cancer presents a challenging prognosis, marked by a five-year overall survival rate of merely 12.5%. Diagnosis frequently occurs at an advanced stage, characterized by ...
Computational biologists have uncovered how RNA splicing -- a crucial process for isoform expression and protein diversity -- is regulated across different cell types in the peripheral blood. This ...
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Researchers discovered how to turn on cancer’s 'kill switch'
Cells have a natural editing system that allows them to rearrange genetic instructions to create different proteins from the ...
Krainer and colleagues reveal details about how the protein SRSF1 can promote cancer, via its function as a regulator of alternative splicing of gene messages. One gene called CASC4, whose splice ...
In a new study, researchers demonstrate that deregulation of a protein called RBFOX2, involved in RNA splicing, contributes to the progression and metastasis of pancreatic cancer. Pancreatic cancer ...
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