Most organic drugs contain one acid group, usually a carboxylic acid, -COOH, or one basic primary, secondary, or tertiary amino group, NC 1-3, [3,22,27,28,29] that determines the acid-base reactivity ...
When the dilution or mixing of the salt or ionized forms of organic drugs results in precipitation, the most likely cause is formation of the nonionized drug forms. Yet, for example, when ceftriaxone ...
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